AB2036
Anti-Collagen Type II Antibody
Chemicon®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
radioimmunoassay: suitable
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
rat ... Col2A1(25412)
Specificity
Rat type II Collagen. The antibody shows less than 0.1% reactivity with rat Collagen Types I, III, V, rat Elastin and Fibronectin.
Immunogen
Collagen Type II extracted and purified from rat fetal cartilage.
Application
Immunohistochemistry: 1:40 dilution for immunofluorescent staining of frozen rat articular cartilage tissue. The antibody is also reactive on paraffin embedded rat cartilage tissues at a dilution of 1:250 using an ABC detection system.
Radioimmunoassay
ELISA: 1:100-1:200
Optimal working dilutions must be determined by end user.
Radioimmunoassay
ELISA: 1:100-1:200
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
This Anti-Collagen Type II Antibody is validated for use in ELISA, RIA, IH, IH(P) for the detection of Collagen Type II.
Physical form
Format: Purified
IgG fraction. Liquid at 1.0 mg/mL in 0.01M phosphate, 0.09M NaCl, pH 7.2
Storage and Stability
Maintain frozen at -20°C for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yorikazu Akatsu et al.
Cell and tissue research, 375(2), 425-435 (2018-09-28)
The objectives of this study are (1) to examine age-dependent longitudinal differences in histological responses after creation of partial-thickness articular cartilage defects (PTCDs) in rats and to use this model (2) to objectively evaluate the effectiveness of interventions for cartilage
Olimpia Ortiz-Arrabal et al.
Biomedicines, 9(7) (2021-08-07)
Because cartilage has limited regenerative capability, a fully efficient advanced therapy medicinal product is needed to treat severe cartilage damage. We evaluated a novel biomaterial obtained by decellularizing sturgeon chondral endoskeleton tissue for use in cartilage tissue engineering. In silico
Ana Belén Bonhome-Espinosa et al.
Journal of the mechanical behavior of biomedical materials, 104, 103619-103619 (2020-03-17)
The encapsulation of cells into biopolymer matrices enables the preparation of engineered substitute tissues. Here we report the generation of novel 3D magnetic biomaterials by encapsulation of magnetic nanoparticles and human hyaline chondrocytes within fibrin-agarose hydrogels, with potential use as
Li Zou et al.
Scientific reports, 6, 22868-22868 (2016-03-17)
Human pluripotent stem cells provide a standardized resource for bone repair. However, criteria to determine which exogenous cells best heal orthopedic injuries remain poorly defined. We evaluated osteogenic progenitor cells derived from both human embryonic stem cells (hESCs) and induced
David Sánchez-Porras et al.
Biomedicines, 9(3) (2021-04-04)
Considering the high prevalence of cartilage-associated pathologies, low self-repair capacity and limitations of current repair techniques, tissue engineering (TE) strategies have emerged as a promising alternative in this field. Three-dimensional culture techniques have gained attention in recent years, showing their
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