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AB1581

Sigma-Aldrich

Anti-Vasoactive Intestinal Peptide Antibody

serum, Chemicon®

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Synonym(s):
VIP
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

sheep

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

guinea pig, rabbit, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

guinea pig ... Vip(100735454)
rat ... Vip(117064)

Specificity

Vasoactive Intestinal Peptide (VIP).

Immunogen

Synthetic peptide (1-28) coupled to KLH with glutaraldehyde.

Application

Anti-Vasoactive Intestinal Peptide Antibody detects level of Vasoactive Intestinal Peptide & has been published & validated for use in IH.
Immunohistochemistry: 1:1000

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

Physical form

Sheep serum. Lyophilized, no preservatives. Reconstitute with 100 μL of sterile distilled water. Centrifuge to remove any residue.

Storage and Stability

Maintain at -20 to -70°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

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Bao Nan Chen et al.
The Journal of comparative neurology, 523(5), 742-756 (2014-11-08)
Extrinsic nerves to the gut influence the absorption of water and electrolytes and expulsion of waste contents, largely via regulation of enteric neural circuits; they also contribute to control of blood flow. The distal colon is innervated by extrinsic sympathetic
Dale F Sharrad et al.
The Journal of comparative neurology, 521(3), 657-676 (2012-07-24)
Parkinson's disease is a neurodegenerative disorder characterized by motor and nonmotor impairments, including constipation. The hallmark pathological features of Parkinson's disease are Lewy bodies and neurites, of which aggregated α-synuclein is a major constituent. Frequently, Lewy pathology is identified in
Dale F Sharrad et al.
The Journal of comparative neurology, 521(11), 2523-2537 (2013-01-09)
Parkinson's disease is a neurodegenerative disorder characterized by Lewy bodies and neurites composed mainly of the presynaptic protein α-synuclein. Frequently, Lewy bodies and neurites are identified in the gut of Parkinson's disease patients and may underlie associated gastrointestinal dysfunctions. We
Spatiotemporal distribution of vasoactive intestinal polypeptide receptor 2 in mouse suprachiasmatic nucleus.
An, S; Tsai, C; Ronecker, J; Bayly, A; Herzog, ED
The Journal of Comparative Neurology null
Guo-Du Wang et al.
American journal of physiology. Gastrointestinal and liver physiology, 291(5), G928-G937 (2006-10-13)
Platelet-activating factor (PAF) is a proinflammatory mediator that may influence neuronal activity in the enteric nervous system (ENS). Electrophysiology, immunofluorescence, Western blot analysis, and RT-PCR were used to study the action of PAF and the expression of PAF receptor (PAFR)

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