AB1427
Anti-Interleukin-8 Antibody
Chemicon®, from rabbit
Synonym(s):
IL-8
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CXCL8(3576)
General description
Interleukin-8 (IL-8) is a chemokine produced by macrophages, epithelial cells and endothelial cells. IL-8′s primary function is to recruit neutrophils to phagocytose the antigen which trigger the antigen pattern toll-like receptors. IL-8 can be secreted by any cells with toll-like receptors which are involved in a body’s innate immune response. Once IL-8 is secreted, it becomes an important mediator of immune reaction and inflammatory response. IL-8’s monomer and homodimer forms are both inducers of CXCR1 and CXCR2. IL-8 is also believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection.
Specificity
Reacts with human IL-8.
No reactivity to IL-1alpha, IL-1beta, IL-2, IL-3, IL4, IL-6, IL-7, IL-10, MIP-1alpha, TNFalpha, GM-CSF and IgG WHO standards by EIA.
No reactivity to IL-1alpha, IL-1beta, IL-2, IL-3, IL4, IL-6, IL-7, IL-10, MIP-1alpha, TNFalpha, GM-CSF and IgG WHO standards by EIA.
Immunogen
Recombinant human IL-8.
Application
Anti-Interleukin-8 Antibody is an antibody against Interleukin-8 for use in ELISA & WB.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Western blot: A 1:1000-1:3000 dilution of anti-interleukin-8 (IL-8) detected recombinant human IL-8.
ELISA: A recommended dilution range of 1:100-1:1000 of anti-interleukin-8 (IL-8) was used on recombinant IL-8.
Final working dilutions must be determined by end user.
ELISA: A recommended dilution range of 1:100-1:1000 of anti-interleukin-8 (IL-8) was used on recombinant IL-8.
Final working dilutions must be determined by end user.
Quality
Routinely evaluated by western blot on recombinant human IL-8.
Target description
11 kDa
Physical form
Format: Purified
Liquid in PBS, no preservatives.
Protein A purified
Storage and Stability
Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service