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AB10527

Sigma-Aldrich

Anti-VDAC Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

voltage-dependent anion channel 1, Porin 31HL, Outer mitochondrial membrane protein porin 1, PORIN-31-HL, Porin 31HM, voltage-dependent anion-selective channel protein 1, Plasmalemmal porin

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, pig, mouse, human, horse

species reactivity (predicted by homology)

rhesus macaque (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), bovine (based on 100% sequence homology), equine (based on 100% sequence homology), porcine (based on 100% sequence homology)

packaging

antibody small pack of 25 μg

technique(s)

western blot: suitable

NCBI accession no.

NP_003365

UniProt accession no.

P21796

shipped in

ambient

Gene Information

human ... VDAC1(7416)

General description

Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.

Immunogen

KLH-conjugated linear peptide corresponding to human VDAC.

Application

Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
This Anti-VDAC Antibody is validated for use in WB for the detection of VDAC.

Quality

Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected VDAC in 10 µg of HepG2 cell lysate.

Target description

~33 kDa observed

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
HepG2 cell lysate

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Pricing

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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