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8.55126

Sigma-Aldrich

NovaPEG amino resin

Novabiochem®

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About This Item

UNSPSC Code:
51171641

product line

NovaPEG
Novabiochem®

Quality Level

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

A remarkable totally PEG-based resin for solid phase peptide synthesis. The support has excellent swelling properties in a wide range of solvents, including water, MeCN, MeOH, DCM, DMF, THF, and toluene. In comparative studies this resin was found to give better results than polystyrene-based supports in the synthesis of hydrophobic peptides. The high hydrophilicity was also found to benefit on-resin immunoassays with one-bead-one-peptide libraries [1].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] F. Garcia-Martin, et al. (2006) J. Comb. Chem., 8, 213.

Linkage

Replaces: 01-64-0485

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.45 - 1.00 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(C)

Not applicable

Regulatory Information

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