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Sigma-Aldrich

Aminomethylated polystyrene LL (100-200 mesh)

Novabiochem®

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Synonym(s):
AM resin LL (100-200 mesh)
UNSPSC Code:
13111023
NACRES:
NA.22

Quality Level

200

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

Related Categories

General description

Novabiochem™′s AM resin is prepared according to optimized protocols by direct aminomethylation of polystyrene [1]. This process gives a highly homogeneous and chemically defined support free from potentially reactive chloromethyl groups. This resin can be easily acylated with any appropriate carboxylic acid-containing linker using standard methods of amide bond formation to furnish supports for both Boc and Fmoc batch SPPS and SPOS.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 01-64-0447

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
TNBS-Test (positive): passes test
TNBS-Test (after loading with Fmoc-Leu-OH (negative)): passes test
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
TMAX is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Base Resins for Peptide Synthesis

Novabiochem® offers polymer supports for solid phase peptide synthesis, suitable for various peptide lengths and sequences.

Protocols

Boc Resin Cleavage Protocol

Anhydrous HF is the preferred reagent for peptide cleavage from Boc-based resins, versatile and effective for various peptide synthesis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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