Recommended Products
Quality Level
product line
Novabiochem®
form
beads
reaction suitability
reaction type: solution phase peptide synthesis
reactivity: alcohol reactive
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
2-8°C
Related Categories
General description
This polymer-bound version of IBX cleanly converts primary and secondary alcohols to the corresponding aldehydes and ketones [1,2]. It is particularly useful for the synthesis of peptide aldehydes as it oxidises peptide alcohols efficiently and spent resin can be simply removed by filtration.
Literature references
[1] G. Sorg, et al. (2001) Angew. Chem. Int. Ed., 40, 4395.
[2] G. Sorg, et al. (2005) J. Pept. Sci.,11, 147.
Literature references
[1] G. Sorg, et al. (2001) Angew. Chem. Int. Ed., 40, 4395.
[2] G. Sorg, et al. (2005) J. Pept. Sci.,11, 147.
Application
- 2-Iodoxybenzoic Acid: An Oxidant for Functional Group Transformations: This study discusses the use of IBX for various organic transformations, including the oxidation of silyl enol ethers and the preparation of polystyrene supported periodinane reagent. (Nair, 2020).
Linkage
Replaces: 01-64-0445
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of iodine): 0.90 - 1.50 mmol/g
Oxidation of Cinnamyl alcohol to Cinnamaldehyde (2 eq. IBX PS): ≥ 90 %
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh.
Appearance of substance (visual): beads
Loading (determined by elemental analysis of iodine): 0.90 - 1.50 mmol/g
Oxidation of Cinnamyl alcohol to Cinnamaldehyde (2 eq. IBX PS): ≥ 90 %
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
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