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8.55006

Sigma-Aldrich

MBHA resin HL (100-200 mesh) . HCl

Novabiochem®

Synonym(s):

4-Methylbenzhydrylamine resin HL (100-200 mesh) hydrochloride salt

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About This Item

UNSPSC Code:
13111023
NACRES:
NA.22

Quality Level

200

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

Related Categories

General description

High load resin for the synthesis of peptide amides by Boc SPPS [1,2]. Carboxylic acids or amino acids can be attached using standard methods of amide bond formation. Cleavage of the carboxamides from this resin can be effected by treatment with HF or TFMSA.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 01-64-0042

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.80 - 1.40 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
The polyer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

Boc Resin Cleavage Protocol

Anhydrous HF is the preferred reagent for peptide cleavage from Boc-based resins, versatile and effective for various peptide synthesis.

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