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Merck
CN

8.53069

Boc-3,4-dehydro-Pro-OH

Novabiochem®

Synonym(s):

Boc-3,4-dehydro-Pro-OH, N-α-t.-Boc-3,4-dehydro-L-proline

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About This Item

Empirical Formula (Hill Notation):
C10H15NO4
CAS Number:
Molecular Weight:
213.23
UNSPSC Code:
12352209
MDL number:
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Product Name

Boc-3,4-dehydro-Pro-OH, Novabiochem®

InChI

1S/C10H15NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h4-5,7H,6H2,1-3H3,(H,12,13)/t7-/m0/s1

InChI key

BMIGSRMSSCUMAZ-ZETCQYMHSA-N

product line

Novabiochem®

assay

≥97% (TLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

2-30°C

Quality Level

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -275.0 - -225.0 °
Purity (TLC(011A)): ≥ 97 %
Purity (TLC(0811)): ≥ 97 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

General description

Standard building block for introduction of dehydroproline amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Other Notes

Replaces: 04-12-0128

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk

WGK 3

Storage Class

11 - Combustible Solids

Regulatory Information

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Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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