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8.53002

Sigma-Aldrich

Boc-Leu-OH . H₂O

Novabiochem®

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Synonym(s):
Boc-Leu-OH . H₂O, N-α-t.-Boc-L-leucine hydrate
Empirical Formula (Hill Notation):
C11H21NO4 · xH2O
CAS Number:
Molecular Weight:
231.29 (anhydrous basis)
UNSPSC Code:
12352209
EC Index Number:
236-073-2
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

2-30°C

InChI

1S/C11H21NO4.H2O/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5;/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14);1H2/t8-;/m0./s1

InChI key

URQQEIOTRWJXBA-QRPNPIFTSA-N

General description

Standard building block for introduction of leucine amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Linkage

Replaces: 04-12-0005

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=2 AcOH): -26.5 - -21.5 °
Purity (TLC(011A)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Protocols

Anhydrous HF is the preferred reagent for peptide cleavage from Boc-based resins, versatile and effective for various peptide synthesis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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