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Merck
CN

8.52308

Fmoc-hGlu(OtBu)-OH

Novabiochem®

Synonym(s):

Fmoc-hGlu(OtBu)-OH, Fmoc-L-α-homoglutamic acid 6-t-butyl ester,(S)-2-(Fmoc-amino)adipic acid 6-t-butyl ester

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About This Item

Empirical Formula (Hill Notation):
C25H29NO6
CAS Number:
Molecular Weight:
439.50
MDL number:
UNSPSC Code:
12352209
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Product Name

Fmoc-hGlu(OtBu)-OH, Novabiochem®

form

solid

SMILES string

N([C@@H](CCCC(=O)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C25H29NO6/c1-25(2,3)32-22(27)14-8-13-21(23(28)29)26-24(30)31-15-20-18-11-6-4-9-16(18)17-10-5-7-12-19(17)20/h4-7,9-12,20-21H,8,13-15H2,1-3H3,(H,26,30)(H,28,29)/t21-/m0/s1

InChI key

FFLAQPKWVSSKJC-NRFANRHFSA-N

product line

Novabiochem®

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

108-112 °C

application(s)

peptide synthesis

functional group

carboxylic acid

storage temp.

2-8°C

Quality Level

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

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General description

A useful homolog of glutamic acid for the study of protein-protein interactions, tumor targeting, and SAR studies [1,2].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

[1] R. Carpenter, et al. (2007) J. Med. Chem., 23, 5863.
[2] P. Li, et al. (2006) Nat. Chem. Biol., 7, 381.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品
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