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8.52156

Sigma-Aldrich

Fmoc-D-Ser(tBu)-OH

≥99.0% (HPLC), for peptide synthesis, Novabiochem®

Synonym(s):

Fmoc-D-Ser(tBu)-OH, N-α-Fmoc-O-t.-butyl-D-serine

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About This Item

Empirical Formula (Hill Notation):
C22H25NO5
CAS Number:
Molecular Weight:
383.44
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

product name

Fmoc-D-Ser(tBu)-OH, Novabiochem®

Quality Level

product line

Novabiochem®

Assay

≥97.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

120-130 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

InChI

1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m1/s1

InChI key

REITVGIIZHFVGU-LJQANCHMSA-N

General description

Standard building block of introduction of D-serine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-13-1052

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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