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8.52130

Sigma-Aldrich

Fmoc-Tyr(tBu)-OPfp

Novabiochem®

Synonym(s):

Fmoc-Tyr(tBu)-OPfp, N-α-Fmoc-O-t.-butyl-L-tyrosine pentafluorophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C34H28F5NO5
CAS Number:
Molecular Weight:
625.58
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

60-70 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

15-25°C

InChI

1S/C34H28F5NO5/c1-34(2,3)45-19-14-12-18(13-15-19)16-25(32(41)44-31-29(38)27(36)26(35)28(37)30(31)39)40-33(42)43-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,40,42)/t25-/m0/s1

InChI key

ADOSTZDWXCEVJP-VWLOTQADSA-N

General description

Pre-formed pentafluorophenyl ester for coupling of tyrosine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1519

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -17.5 - -12.5 °
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): ≥ 98.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Information

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