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8.52074

Sigma-Aldrich

Fmoc-Dab(Boc)-OH

Novabiochem®

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Synonym(s):
Fmoc-Dab(Boc)-OH, N-α-Fmoc-N-γ-t.-Boc-L-diaminobutanoic acid
Empirical Formula (Hill Notation):
C24H28N2O6
CAS Number:
Molecular Weight:
440.49
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥94.0% (acidimetric)
≥97.0% (HPLC)
≥98% (TLC)
≥98% (perchloric acid titration)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Boc
amine

storage temp.

2-30°C

InChI

1S/C24H28N2O6/c1-24(2,3)32-22(29)25-13-12-20(21(27)28)26-23(30)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m0/s1

InChI key

LIWKOFAHRLBNMG-FQEVSTJZSA-N

General description

Standard building block for introduction of diaminobutyric acid amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1160

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(0711)): ≥ 98 %
Purity (TLC(BAWP)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 94.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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