8.52031
Fmoc-Cys(Mmt)-OH
≥99% (TLC), for peptide synthesis, Novabiochem®
Synonym(s):
Fmoc-Cys(Mmt)-OH, N-α-Fmoc-S-p-methoxytrityl-L-cysteine
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About This Item
Recommended Products
Product Name
Fmoc-Cys(Mmt)-OH, Novabiochem®
Quality Level
product line
Novabiochem®
Assay
≥85.0% (acidimetric)
≥98.0% (HPLC)
≥99% (TLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
thiol
storage temp.
15-25°C
Related Categories
1 of 4
This Item | 852373 | 852089 | 852417 |
|---|---|---|---|
| functional group thiol | functional group thiol | functional group amine | functional group thiol |
| assay ≥85.0% (acidimetric), ≥99% (TLC), ≥98.0% (HPLC) | assay - | assay ≥95% (TLC), ≥95.0% (HPLC) | assay - |
| product line Novabiochem® | product line Novabiochem® | product line Novabiochem® | product line Novabiochem® |
| storage temp. 15-25°C | storage temp. 15-25°C | storage temp. 15-25°C | storage temp. 15-25°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
General description
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Cysteine-Containing Peptides
Literature references
[1] K. Barlos, et al. in ′Peptides 1992, Proc. 22nd European Peptide Symposium′, C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283.
[2] C. Kellenberger, et al. (1995) Pept. Res., 8, 321.
[3] K. Barlos, et al. (1996) Int. J. Peptide Protein Res., 47, 148.
[4] A. K. Galande, et al. (2005) J. Comb. Chem., 7, 174.
Application
- An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide: Details the use of Fmoc-Cys(Mmt)-OH in the synthesis of Eptifibatide, highlighting its role in a cGMP-ready process (Sabatino et al., 2020).
Linkage
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 99 %
Purity (TLC(0811)): ≥ 99 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 85.0 %
Water (K. F.): ≤ 1.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
Certificates of Analysis (COA)
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Articles
Novabiochem® offers orthogonally protected amino acids for peptide synthesis, including cyclic and branched peptides.
Protocols
Overcome challenges in synthesis and disulfide bond formation with protocols for Fmoc solid-phase peptide synthesis of peptides with cysteine and methionine.
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