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Merck
CN

8.52012

Sigma-Aldrich

Fmoc-Lys(Boc)-OH

Novabiochem®

Synonym(s):

Fmoc-Lys(Boc)-OH, N-α-Fmoc-N-ε-t.-Boc-L-lysine

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Select a Size

25 G
¥653.30
100 G
¥1,642.90
250 G
¥3,273.05
500 G
¥6,274.25
1 KG
¥12,289.67
8520122000
¥23,544.50
8520125000
¥54,979.97

¥653.30


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25 G
¥653.30
100 G
¥1,642.90
250 G
¥3,273.05
500 G
¥6,274.25
1 KG
¥12,289.67
8520122000
¥23,544.50
8520125000
¥54,979.97

About This Item

Empirical Formula (Hill Notation):
C26H32N2O6
CAS Number:
Molecular Weight:
468.54
MDL number:
UNSPSC Code:
12352209
EC Index Number:
276-256-4
NACRES:
NA.22

¥653.30


Please contact Customer Service for Availability

Request a Bulk Order

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)
≥98.0% (acidimetric)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

123-130 °C

application(s)

peptide synthesis

functional group

Boc
amine

storage temp.

2-30°C

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This Item
852146852013852023
functional group

Boc, amine

functional group

amine

functional group

amine

functional group

amine

assay

≥98% (TLC), ≥99.0% (HPLC), ≥98.0% (acidimetric)

assay

≥97.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

assay

≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

assay

≥97.0% (HPLC), ≥98% (TLC)

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

storage temp.

2-30°C

storage temp.

15-25°C

storage temp.

2-30°C

storage temp.

2-30°C

mp

123-130 °C

mp

120-130 °C

mp

105-115 °C

mp

-

General description

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of lysine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Application


  • Pharmacokinetics of Tizanidine in Muscle Spasticity: A comprehensive review on Tizanidine covers its pharmacological advancements and therapeutic applications, particularly focusing on muscle spasticity. This highlights the relevance of high-purity Tizanidine-D₄ hydrochloride in creating precise and reproducible pharmacokinetic profiles (Zhu et al., 2024).

  • Stable Isotope-Labeled Tizanidine for Bioanalytical Method Development: The development and validation of bioanalytical methods for monitoring drug interactions and metabolism extensively utilize Tizanidine-D₄ HCl. The isotopic labeling aids in accurate quantification and identification, enhancing the reliability of pharmacokinetic and pharmacodynamic studies (Chen et al., 2024).

  • Tizanidine-D₄ Hydrochloride Solution for Receptor Binding Studies: The application of Tizanidine-D₄ in receptor binding studies is inferred from research exploring its withdrawal effects and the pharmacological interventions required, suggesting its utility in detailed receptor interaction studies in clinical settings (Tanimura et al., 2024).


Linkage

Replaces: 04-12-1026

Analysis Note

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Lys(Boc)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Lys(Boc)-Lys(Boc)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Lys-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Yun Song et al.
Cell reports, 30(8), 2699-2711 (2020-02-27)
The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the

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