8.51221
PyAOP
for peptide synthesis, Novabiochem®
Synonym(s):
PyAOP, (7-Azabenzotriazol-1-yloxy)trispyrrolidinophosphonium hexafluorophosphate
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About This Item
Product Name
PyAOP, Novabiochem®
SMILES string
F[P-](F)(F)(F)(F)F.[P](=[N+]5CCCC5)(N4CCCC4)(N3CCCC3)O[n]1nnc2c1nccc2
InChI
1S/C17H27N7OP.F6P/c1-2-11-21(10-1)26(22-12-3-4-13-22,23-14-5-6-15-23)25-24-17-16(19-20-24)8-7-9-18-17;1-7(2,3,4,5)6/h7-9H,1-6,10-15H2;/q+1;-1
InChI key
CBZAHNDHLWAZQC-UHFFFAOYSA-N
product line
Novabiochem®
form
powder
reaction suitability
reaction type: Coupling Reactions
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
-10 to -25°C
Quality Level
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Application
- In the synthesis of N,N′-substituted acylguanidines by solid-phase peptide synthesis.
- To facilitate the formation of peptide bonds during the synthesis of cyclic peptide hybrids.
General description
Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents
Literature references:
[1] F. Albericio, et al. (1997) Tetrahedron Lett., 38, 4853.
Legal Information
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Novabiochem® coupling reagents for in situ activation are fast-reacting and compatible with various amino acids.
Novabiochem®可提供大量的偶联剂用于原位活化。原位活化试剂易于使用 - 即使是利用空间位阻氨基酸，并且它们的使用通常没有副反应。
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