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Sigma-Aldrich

K-Oxyma Pure

Novabiochem®

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Synonym(s):
K-Oxyma Pure, (Z)-ethyl 2-cyano-3-hydroxyacrylate potassium salt
Empirical Formula (Hill Notation):
C5H5KN2O3
CAS Number:
Molecular Weight:
180.20
MDL number:
UNSPSC Code:
12352107
NACRES:
NA.22

Quality Level

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

mp

145-155 °C

application(s)

peptide synthesis

storage temp.

2-8°C

General description

A version of Oxyma Pure with improved solubility in DMF, This potassium salt when used in conjunction with DIPCDI does not cause premature cleavage of peptides from the hyperacid-sensitive 2-chlorotrityl resin [1].

Literature references

[1] P. Cherkupally, et al. (2013) Eur. J. Org. Chem., 6372.

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 145 °C
Melting range (upper value): ≤ 155 °C
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 2.0 %
Identity (Potassium): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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