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8.51206

Sigma-Aldrich

TSTU

≥97.0% (NMR), for peptide synthesis, Novabiochem®

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Synonym(s):
TSTU, N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate, O-[N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate
Empirical Formula (Hill Notation):
C9H16BF4N3O3
CAS Number:
Molecular Weight:
301.05
MDL number:
UNSPSC Code:
12352107
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥97.0% (NMR)

form

powder or crystals

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

mp

195-200 °C

application(s)

peptide synthesis

storage temp.

2-8°C

InChI

1S/C9H16N3O3.BF4/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;2-1(3,4)5/h5-6H2,1-4H3;/q+1;-1

InChI key

YEBLHMRPZHNTEK-UHFFFAOYSA-N

General description

Useful reagent for the conversion of carboxylic acids to water soluble OSu esters [1, 2]. Ideal for the conversion of dyes and PEG building blocks to the corresponding active esters for coupling in aqueous media.

Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents

Literature references

[1] W. Bannwarth, et al. (1988) Helv. Chim. Acta, 71, 2085.
[2] R. Knorr, et al. (1989) Tetrahedron Lett., 30, 1927.

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder to crystals
Purity (NMR): ≥ 97.0 %
Identity (IR): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1A

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

Novabiochem® coupling reagents for in situ activation are fast-reacting and compatible with various amino acids.

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