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Key Documents

Safety Information

8.51015

Sigma-Aldrich

Dde-OH

Novabiochem®

Synonym(s):

Dde-OH, 2-Acetyldimedone

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About This Item

Empirical Formula (Hill Notation):
C10H14O3
CAS Number:
Molecular Weight:
182.22
MDL number:
UNSPSC Code:
12352115
NACRES:
NA.22

To inquire about this product 8.51015, please contact your local Merck office or dealer. Contact Technical Service

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)

form

powder

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

2-8°C

InChI

1S/C10H14O3/c1-6(11)9-7(12)4-10(2,3)5-8(9)13/h12H,4-5H2,1-3H3

InChI key

DIJDAMFZOHSRID-UHFFFAOYSA-N

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This Item
567532U567531U567502U
separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

matrix active group

PFP (pentafluorophenyl) phase

matrix active group

PFP (pentafluorophenyl) phase

matrix active group

PFP (pentafluorophenyl) phase

matrix active group

PFP (pentafluorophenyl) phase

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

agency

suitable for USP L43

agency

suitable for USP L43

agency

suitable for USP L43

agency

suitable for USP L43

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

General description

Reagent for the introduction of the Dde protecting group [1,2,3,4].

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Literature references

[1] B. W. Bycroft, et al. (1993) J. Chem. Soc., Chem. Commun., 778.
[2] I. A. Nash, et al. (1996) Tetrahedron Lett., 37, 2625.
[3] F. Berst, et al. (2000) Tetrahedron Lett., 41, 6649.
[4] A. N. Acharaya, et al. (2001) J. Comb. Chem., 3, 612.

Linkage

Replaces: 01-63-0033

Analysis Note

Color (visual): white to slight yellow to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (DC(012A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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