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Sigma-Aldrich

Adipic dihydrazide

for synthesis

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Synonym(s):
Adipic dihydrazide, Hexanedioic acid dihydrazide
Empirical Formula (Hill Notation):
C6H14N4O2
CAS Number:
Molecular Weight:
174.20
MDL number:
UNSPSC Code:
12352127
EC Index Number:
213-999-5
NACRES:
NA.22

Quality Level

form

powder

autoignition temp.

360 °C

mp

178-182 °C

transition temp

flash point >150 °C

storage temp.

15-25°C

InChI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

InChI key

IBVAQQYNSHJXBV-UHFFFAOYSA-N

Application

<ul>
<li><strong>Comprehensive repair strategy in infected wound healing:</strong> Adipic dihydrazide is used in the formation of the GA/OKGM/MT hydrogel through a Schiff base reaction with modified gelatin (GA) to create an effective wound dressing with rapid hemostatic properties and the ability to promote fibroblast proliferation and migration, leading to accelerated wound healing (Qiu et al., 2024).</li>
<li><strong>Photothermally triggered shape memory polymers:</strong> Adipic dihydrazide was utilized in the cross-linking of porphyrin-based amphiphilic copolymer self-assemblies to create photothermally triggered one-component shape memory polymers, indicating potential for advanced material designs (Song et al., 2022).</li>
<li><strong>Alleviating osteoarthritis with hydrogels:</strong> Adipic dihydrazide is utilized in the formation of the HA/PRP/BM hydrogel through a Schiff base reaction with hyaluronic acid (HA), resulting in a self-healing hydrogel with properties tailored for cartilage protection and lubrication in the articular cavity (Zhou et al., 2022).</li>
</ul>

Analysis Note

Assay (HClO₄): ≥ 97,0 %(m)
Melting range (lower value): ≥ 178 °C
Melting range (upper value): ≤ 182 °C
Identity (IR): conforms

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup


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