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8.20610

Sigma-Aldrich

Glyoxal

(40% solution in water) for synthesis

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About This Item

UNSPSC Code:
12352114
NACRES:
NA.22

vapor pressure

20.2 hPa ( 20 °C)

Quality Level

autoignition temp.

285 °C

potency

2000-5000 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

pH

2-3 (20 °C in H2O)

bp

104 °C/1013 hPa

mp

-14 °C

density

1.27 g/cm3 at 20 °C

storage temp.

2-30°C

Application


  • HFIP-Mediated Multicomponent Reactions: Research demonstrates the use of HFIP (Hexafluoroisopropanol) in synthesizing pyrazole-linked thiazole derivatives, highlighting a new application in organic synthesis. Glyoxal is instrumental in the development of these multifunctional structures, contributing to advanced material design (Banerjee et al., 2024).

  • Peptide Stapling in Protein Engineering: A study describes peptide stapling techniques using alpha-ketoaldehydes, which crosslink amines through glyoxal-modified linkers. This approach is pivotal in creating stable peptide structures for therapeutic applications (Guo et al., 2024).

Analysis Note

Assay (acidimetric): 39.0 - 41.0 %
Density (d 20 °C/ 4 °C): 1.266 - 1.271

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1


Certificates of Analysis (COA)

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