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8.20261

Sigma-Aldrich

8-Hydroxyquinoline

for synthesis

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Synonym(s):
8-Hydroxyquinoline, Oxine, 8-Quinolinol
Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
148-24-3
Molecular Weight:
145.16
MDL number:
MFCD00006807
UNSPSC Code:
12352104
EC Index Number:
205-711-1
NACRES:
NA.22

Quality Level

200

Assay

≥99.0% (GC)

form

solid

potency

1200 mg/kg LD50, oral (Rat)

reaction suitability

reaction type: Addition Reactions

bp

267 °C/1013 hPa

mp

72.5-74.0 °C

solubility

555 mg/L

density

1.034 g/cm3 at 20 °C

application(s)

peptide synthesis

storage temp.

2-30°C

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChI key

MCJGNVYPOGVAJF-UHFFFAOYSA-N

Related Categories

Application

<ul>
<li><strong>8-Hydroxyquinoline in luminescent cocrystals for analytical detection:</strong> 8-Hydroxyquinoline is used as an electron donor during the development of luminescent organic cocrystal for the detection of 2,4-dinitroaniline, demonstrating its utility in analytical chemistry applications (Liu et al., 2024).</li>
<li><strong>Extraction and determination of pesticides using 8-Hydroxyquinoline functionalized nanocomposites:</strong> Poly(8-hydroxyquinoline) were utilized for the extraction and determination of organophosphorus pesticides in various environmental samples, showcasing its application in environmental monitoring (Shahsavani and Fakhari, 2024).</li>
<li><strong>8-Hydroxyquinoline in medical imaging and therapy:</strong> 8-Hydroxyquinoline is used as a Schiff base derivative and an auxiliary ligand in the synthesis of the dinuclear lanthanide complex [Ho2(L)2(acac)2(CH3OH)2] (Cong et al., 2024).</li>
</ul>

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 71 °C
Melting range (upper value): ≤ 74 °C
Identity (IR): passes test

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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