8.18586
Isophorone diisocyanate
(mixture of cis- and trans-isomers) for synthesis
Recommended Products
vapor pressure
0.0004 hPa ( 20 °C)
Quality Level
Assay
≥99.0% (GC)
form
liquid
autoignition temp.
430 °C
potency
4825 mg/kg LD50, oral (Rat)
>7000 mg/kg LD50, skin (Rat)
expl. lim.
0.7-4.5 % (v/v)
bp
158-159 °C/13 hPa
mp
-60 °C
transition temp
flash point 155 °C
solubility
0.015 g/L (slow decomposition)
density
1.06 g/cm3 at 20 °C
storage temp.
2-30°C
InChI
1S/C12H18N2O2/c1-11(2)4-10(14-9-16)5-12(3,6-11)7-13-8-15/h10H,4-7H2,1-3H3
InChI key
NIMLQBUJDJZYEJ-UHFFFAOYSA-N
Application
- Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery.: This study explores the development of thermoresponsive random poly(ether urethanes) synthesized using Isophorone diisocyanate. These polymers exhibit adjustable lower critical solution temperatures (LCSTs), making them suitable for controlled anticancer drug delivery applications. The research highlights the potential of Isophorone diisocyanate in creating advanced materials for medical use, specifically in drug delivery systems (Sardon et al., 2015).
Analysis Note
Density (d 20 °C/ 4 °C): 1.060 - 1.062
Identity (IR): passes test
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 1 Inhalation - Aquatic Chronic 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 2
Flash Point(F)
325.4 °F - closed cup
Flash Point(C)
163 °C - closed cup
Regulatory Information
Certificates of Analysis (COA)
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