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8.17007

SAFC

Polyethylene glycol

6000, EMPROVE® ESSENTIAL, Ph. Eur., NF

Pharma Manufacturing

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Synonym(s):
Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 6000, PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
13111021
EC Index Number:
500-038-2

Agency

NF
Ph. Eur.

Quality Level

500

vapor pressure

<0.01 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

420 °C

mol wt

average Mn 6000

technique(s)

API processing | nano-milling: suitable

pH

5-7 (20 °C, 100 g/L in H2O)

mp

58-63 °C

transition temp

flash point 270 °C

solubility

550 g/L

density

1.2 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

storage temp.

15-25°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Certificates of Analysis (COA)

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