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8.08610

Sigma-Aldrich

2,2,2-Trichloroethanol

for synthesis

Synonym(s):

2,2,2-Trichloroethanol, ß,ß,ß-Trichloroethyl alcohol

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About This Item

Empirical Formula (Hill Notation):
C2H3Cl3O
CAS Number:
Molecular Weight:
149.40
MDL number:
UNSPSC Code:
12352104
EC Index Number:
204-071-0
NACRES:
NA.22

vapor pressure

1.3 hPa ( 20 °C)

Quality Level

Assay

≥97.0% (GC)

form

liquid

autoignition temp.

151 °C

potency

600 mg/kg LD50, oral (Rat)

pH

5-6 (20 °C in H2O, saturated solution)

bp

151-153 °C/1013 hPa

mp

17-18 °C

transition temp

flash point >110 °C

density

1.56 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2

InChI key

KPWDGTGXUYRARH-UHFFFAOYSA-N

Application



  • Assessment of EDDP Perchlorate Stability in Biological Samples: An investigation focused on the stability of methaDoneand its main metabolite, EDDP perchlorate, in oral fluids. The study highlighted the importance of understanding metabolite stability for accurate drug testing and monitoring in forensic and clinical settings (Fucci and De Giovanni, 2008).


  • EDDP Perchlorate in Drug Testing: EDDP perchlorate was examined in a forensic context using the SPME technique to simultaneously detect multiple drugs of abuse in saliva. This method underscores the utility of EDDP perchlorate as a reliable biomarker in toxicology studies and drug monitoring (Fucci, De Giovanni, and Chiarotti, 2003).


  • Pharmacological Action of MethaDoneand Metabolites: Research explored the interaction of methaDoneand its metabolites, including EDDP perchlorate, with rat alpha3beta4 nicotinic receptors. These findings contribute to the understanding of the pharmacodynamic properties of methadone′s metabolites, relevant in the development of therapeutic and diagnostic strategies (Xiao et al., 2001).

Analysis Note

Assay (GC, area%): ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.551 - 1.561
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup


Certificates of Analysis (COA)

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