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Safety Information

8.03010

Sigma-Aldrich

Diethylamine

for synthesis

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Synonym(s):
Diethylamine, N-Ethylethanamine
Linear Formula:
(C2H5)2NH
CAS Number:
Molecular Weight:
73.14
MDL number:
UNSPSC Code:
12352116
EC Index Number:
203-716-3
NACRES:
NA.22

vapor pressure

253 hPa ( 20 °C)

Quality Level

Assay

≥99% (GC)

form

liquid

autoignition temp.

290 °C

potency

540 mg/kg LD50, oral (Rat)
582 mg/kg LD50, skin (Rabbit)

expl. lim.

2.0-11.8 % (v/v)

pH

13 (20 °C, 100 g/L in H2O)

bp

56 °C/1013 mbar

mp

-50 °C

transition temp

flash point -23 °C

density

0.71 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C4H11N/c1-3-5-4-2/h5H,3-4H2,1-2H3

InChI key

HPNMFZURTQLUMO-UHFFFAOYSA-N

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Application


  • Chemiresistive Sensor Development: Diethylamine was used to enhance the sensitivity of a chemiresistive sensor for CO2 gas monitoring, demonstrating its utility in environmental and industrial applications (Rath et al., 2024).

  • Supercritical Fluid Chromatography: Aromatic stationary phases were synthesized using diethylamine, evaluated based on the linear solvation energy relationship model, which expanded its application in supercritical fluid chromatography (Ge et al., 2024).

  • Nanoparticle Synthesis: Diethylamine facilitated the sol-gel method modifications for synthesizing silver-silica nanoparticles, enhancing their theranostic potential in cancer treatment (Nikolopoulou et al., 2023).

  • Pharmaceutical Analysis: Diethylamine was key in developing a novel enantioselective high-performance liquid chromatography-mass spectrometry method, applied to differentiate dextro- and levo-methorphan in post-mortem samples, showcasing its critical role in forensic and clinical toxicology (Jorbenadze et al., 2024).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.703 - 0.705
Water (K. F.): ≤ 0.10 %
Identity (IR): passes test

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-14.8 °F - closed cup

Flash Point(C)

-26 °C - closed cup

Regulatory Information

危险化学品

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