Skip to Content
Merck
CN

8.02540

Cobalt(II) chloride anhydrous

for synthesis

Synonym(s):

Cobalt(II) chloride anhydrous, Cobalt dichloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
Cl2Co
CAS Number:
7646-79-9
Molecular Weight:
129.84
UNSPSC Code:
12352302
EC Index Number:
231-589-4
NACRES:
NA.22
MDL number:
MFCD00010938

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Cobalt(II) chloride anhydrous, for synthesis

SMILES string

[Co+2].[Cl-].[Cl-]

InChI

1S/2ClH.Co/h2*1H;/q;;+2/p-2

InChI key

GVPFVAHMJGGAJG-UHFFFAOYSA-L

grade

anhydrous

form

powder

potency

418 mg/kg LD50, oral (Rat)

mp

735 °C

solubility

soluble 585.9 g/L

density

3.36 g/cm3 at 25 °C

storage temp.

2-30°C

Quality Level

200

Analysis Note

Assay (argentometric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %

Application

Cobalt(II) chloride anhydrous (CoCl2) can be used as a catalyst in organic synthesis for the transformation of the various functional groups. For example, synthesis of esters via cleavage of ethers by acyl chlorides; acylation of alcohols and amines by anhydrides; and regioselective cleavage of oxiranes. It is also used to synthesize mixed acetals by the addition reaction between alcohols and vinyl ethers.
CoCl2 can be used as a catalyst:
  • For the dealkylation of tertiary amines.
  • In the synthesis of thioketones and thioaldehydes via thionation of carbonyl compounds in the presence of bis(trimethylsilyl) sulfide.
  • In the oxidation of aromatic and aliphatic aldehydes to carboxylic acids in the presence of molecular oxygen and acetic anhydride.
  • In the stereoselective opening of epoxides with N-substituted anilines.

CoCl2 can also be used as:
  • A precursor to synthesize magnetic cobalt nanorods via decomposition of the cobalt coordination complex.
  • A catalyst to prepare acid anhydrides by the reaction of acid chlorides with carboxylic acids.
  • A reagent in the carbon-carbon bond-forming reactions involving active methylene compounds.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B Inhalation - Eye Dam. 1 - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and magnetic properties of Co nanorod superlattices
Wetz F, et al.
Materials Science and Engineering, C, 27(5-8) (2007)
Cobalt (II) chloride catalyzed syntheses of acid anhydrides from acid chlorides
Srivastava RR and Kabalka GW
Tetrahedron Letters, 33(5) (1992)
Cobalt (II) Chloride
Periasamy M, et al.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service