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672159

Sigma-Aldrich

Urokinase Substrate III, Fluorogenic

Suitable for the quantitative direct fluorescent assay of urokinase.

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Synonym(s):
Urokinase Substrate III, Fluorogenic, Z-GGR-AMC, HCl
Empirical Formula (Hill Notation):
C28H33N7O7 · xHCl
Molecular Weight:
579.60 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.54

Quality Level

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

color

white to off-white

solubility

ethanol: soluble
water: soluble

fluorescence

λex 365-380 nm
λem 430-460 nm

shipped in

ambient

storage temp.

−20°C

General description

Suitable for the quantitative direct fluorescent assay of urokinase activity. Also useful as a substrate for plasminogen activators.
Suitable for the quantitative direct fluorescent assay of urokinase. Also useful as a substrate for plasminogen activators.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Quantitative direct fluorescent assay of urokinase
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Gly-Gly-Arg-AMC, HCl

Reconstitution

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Green, C.D.J. 1986. Thromb. Res.44, 849.
Walker, B., and Elmore, D.T. 1984. Thromb. Res.34, 103.
O’Donnel-Tormey, J., and Quigley, J.P. 1983. Proc. Natl. Acad. Sci. USA 80, 344.
Lottenberg, R., et al. 1981. Methods Enzymol.80, 341.
Pierzchala, P.A., et al. 1979. Biochem. J.183, 555.
Strauss, A.W., et al. 1979. Proc. Natl. Acad. Sci. USA76, 4225.
Zimmerman, M., et al. 1978. Proc. Natl. Acad. Sci. USA75, 750.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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