627624
D-Val-Phe-Lys Chloromethyl Ketone, Dihydrochloride
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC₅₀ = 100 pM for human plasmin) over urokinase.
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Synonym(s):
Plasmin Inhibitor, 2HCl
UNSPSC Code:
12352202
NACRES:
NA.77
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Quality Level
Assay
≥90% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
off-white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC50 = 100 pM for human plasmin) over urokinase.
Selective irreversible inhibitor of plasmin with high selectivity for plasmin over urokinase.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Human plasmin
Human plasmin
Product does not compete with ATP.
Reversible: no
Target IC50: 100 pM for human plasmin
Packaging
Packaged under inert gas
Warning
Toxicity: Standard Handling (A)
Sequence
H-D-Val-Phe-Lys-CMK
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
From Catalog:
Desc. Field- added "(IC₅₀ = 100 pM for human plasmin) "
From Catalog:
Desc. Field- added "(IC₅₀ = 100 pM for human plasmin) "
Other Notes
Woessner, J.F., Jr., et al. 1989. Steroids54, 491.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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