Skip to Content
Merck
CN

6.18729

Trifluoroacetic acid

suitable for chromatography

Synonym(s):

Trifluoroacetic acid solution, TFA

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CF3COOH
CAS Number:
76-05-1
Molecular Weight:
114.02
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
5446934
MDL number:
MFCD00004169

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

SMILES string

OC(=O)C(F)(F)F

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

suitability

suitable for chromatography

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

General description

Trifluoroaceticacid (TFA) is used as an additive in HPLC and LC-MS analyses to improve theseparation of basic compounds.

Application

Trifluoroacetic acid can be used as:
  • Ion-pairing reagent in reversed-phase liquid chromatography (RPLC) for peptide separation.
  • An acidic additive in the mobile phase for chiral supercritical fluid chromatography.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

Regulatory Information

新产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography
De Klerck K, et al.
Journal of Chromatography A, 1234, 72-79 (2012)
Utility of retention prediction model for investigation of peptide separation selectivity in reversed-phase liquid chromatography: impact of concentration of trifluoroacetic acid, column temperature, gradient slope and type of stationary phase
Analytical Chemistry, 82(1), 265-275 (2010)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service