612075
Thyroxine-Binding Globulin, Human
Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin.
Synonym(s):
hTBG
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.25
Quality Level
Assay
≥95.0% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
−20°C
General description
M.W. 54,000-64,000.
Native, human thyroxine-binding globulin. Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with α1-antitrypsin. Its affinity for the hormone is thought to be temperature-sensitive.
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
In 140 mM NaCl, 10 mM Tris, 0.1% NaN₃, pH 8.0. Sterile-filtered.
Preparation Note
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Miura, Y., et al. 1993. Endocrinol. J. 40, 127.
Janssen, O.E., et al. 1992. J. Biol. Chem.267, 13998.
Janssen, O.E., et al. 1992. J. Biol. Chem.267, 13998.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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