609312
Thyroglobulin, Human Thyroid
Synonym(s):
Thyroglobulin, Human Thyroid
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About This Item
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biological source
human thyroid
Quality Level
Assay
≥95% (PAGE)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
2-8°C
1 of 4
This Item | T6830 | T1001 | 341578 |
|---|---|---|---|
| biological source human thyroid | biological source human | biological source bovine thyroid | biological source human plasma |
| form lyophilized | form lyophilized solid | form powder | form lyophilized |
| shipped in wet ice | shipped in - | shipped in - | shipped in wet ice |
| storage condition OK to freeze | storage condition - | storage condition - | storage condition OK to freeze |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
General description
Native thyroglobulin, consisting of two polypeptide monomers of 330 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO4 and GalNAc-6-SO4 residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins. When subjected to native PAGE this protein shows a band at
~660 kDa, representing the dimeric form, and another band at ~330 kDa, representing the monomeric form.
~660 kDa, representing the dimeric form, and another band at ~330 kDa, representing the monomeric form.
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from 20 mM NH₄HCO₃.
Preparation Note
Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Reconstitute in phosphate buffer, containing 150 mM NaCl, pH >7.0.
Other Notes
Rawitch, A.B., et al. 1993. Arch. Biochem. Biophys. 300, 271.
Black, E.G., and Sheppard, M.C. 1991. Clin. Endocrinol. 35, 519.
Spiro, R.G., and Bhoyroo, V.D. 1988. J. Biol. Chem. 263, 14351.
Black, E.G., and Sheppard, M.C. 1991. Clin. Endocrinol. 35, 519.
Spiro, R.G., and Bhoyroo, V.D. 1988. J. Biol. Chem. 263, 14351.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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