567028
SIN-1 hydrochloride
≥98% (HPLC), solid, nitric oxide (NO) donor, Calbiochem®
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SIN-1, Hydrochloride, 3-Morpholinosydnonimine, HCl
C6H10N4O2 · xHCl
Recommended Products
product name
SIN-1, Hydrochloride, Nitric oxide (NO) donor.
Quality Level
Assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 10 mg/mL
ethanol: 10 mg/mL
water: 25 mg/mL
shipped in
ambient
storage temp.
−20°C
InChI
1S/C6H11N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5H,1-4,7H2;1H/q+1;/p-1
InChI key
ZRFWHHCXSSACAW-UHFFFAOYSA-M
General description
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets.
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets. Unstable in aqueous solution.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Nitric oxide (NO) donor
Nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Reconstitution
Unstable in aqueous solution; reconstitute just prior to use. Following reconstitution, aliquot and freeze (-20°C).
From Catalog:
Desc. Field- added "Unstable in aqueous solution."
From Catalog:
Desc. Field- added "Unstable in aqueous solution."
Other Notes
Gow, A.J., et al. 2000. Am. J. Physiol. 278, C1099.
Gergel, D., et al. 1995. J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993. FEBS Lett.315, 139.
Lipton, S.A., et al. 1993. Nature364, 626.
Drummer, C., et al. 1991. Thromb. Res.63, 553.
Omar, B.A., et al. 1990. Free Radical Biol. Med.9, 465
Gergel, D., et al. 1995. J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993. FEBS Lett.315, 139.
Lipton, S.A., et al. 1993. Nature364, 626.
Drummer, C., et al. 1991. Thromb. Res.63, 553.
Omar, B.A., et al. 1990. Free Radical Biol. Med.9, 465
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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