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recombinant
expressed in CHO cells
Quality Level
Assay
≥95% (SDS-PAGE)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<1.5 EU/μg Endotoxins (EU/μg of P-Selectin)
shipped in
wet ice
storage temp.
−20°C
General description
Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium.
Biochem/physiol Actions
Shown to bind to P-selectin ligands on U937 cells.
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from Dulbecco’s D-PBS (containing calcium and magnesium), 1% sorbitol.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Reconstitute at 1 mg/ml in sterile H₂O.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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