540025
Pluronic® F-127, PROTEIN GRADE® Detergent, 10% Solution, Sterile-Filtered
Non-ionic detergent useful for isolation of membrane proteins.
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Synonym(s):
Poloxamer 407, Polyoxypropylenepolyoxyethylene Block Copolymer
Recommended Products
Quality Level
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<200 μM aldehyde
<200 μM peroxide
10%±1 detergent
color
clear
shipped in
ambient
storage temp.
2-8°C
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
Related Categories
General description
Conductivity: <50 µmhos.
Application
- The Influence of Tea Tree Oil on Antifungal Activity and Pharmaceutical Characteristics of Pluronic® F-127 Gel Formulations with Ketoconazole.: This study investigates the effects of tea tree oil on the antifungal properties and pharmaceutical characteristics of Pluronic® F-127 gel formulations containing ketoconazole. The research demonstrated enhanced antifungal activity and improved gel consistency, highlighting the potential of this combination for topical antifungal treatments (Wróblewska et al., 2021).
- Comprehensive and comparative studies on nanocytotoxicity of glyceryl monooleate- and phytantriol-based lipid liquid crystalline nanoparticles.: This article explores the cytotoxicity of different lipid liquid crystalline nanoparticles, including those stabilized by Pluronic F-127. The findings reveal critical insights into the safety profiles of these nanoparticles for biomedical applications (Jagielski et al., 2021).
- Co-stabilization of pioglitazone HCL nanoparticles prepared by planetary ball milling: in-vitro and in-vivo evaluation.: This research focuses on the co-stabilization of pioglitazone HCL nanoparticles using Pluronic F-127, demonstrating its effectiveness in enhancing the stability and bioavailability of the drug in both in-vitro and in-vivo settings (Alshora et al., 2020).
- Dual-responsive (pH/temperature) Pluronic F-127 hydrogel drug delivery system for textile-based transdermal therapy.: This paper presents a novel drug delivery system using Pluronic F-127 hydrogel that responds to both pH and temperature changes. The system is designed for textile-based transdermal therapy, providing controlled drug release (Chatterjee et al., 2019).
- Formulation and evaluation of novel controlled release of topical pluronic lecithin organogel of mefenamic acid.: This study formulates a controlled-release topical gel using Pluronic F-127 and lecithin to deliver mefenamic acid. The research highlights the gel′s potential for sustained drug release and enhanced therapeutic efficacy (Jhawat et al., 2016).
Packaging
Packaged under inert gas
Warning
Toxicity: Standard Handling (A)
Physical form
10% aqueous solution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
PROTEIN GRADE is a registered trademark of Merck KGaA, Darmstadt, Germany
Pluronic is a registered trademark of BASF
WGK
WGK 1
Certificates of Analysis (COA)
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