539610
PKCζ/ι Pseudosubstrate Inhibitor
The PKCζ/ι Pseudosubstrate Inhibitor controls the biological activity of PKCζ/ι. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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PKCζ/ι Pseudosubstrate Inhibitor, SIYRRGARRWRKL, Protein Kinase C ζ/ι Pseudosubstrate Inhibitor, SIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor
C76H128N30O16
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Quality Level
Assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
solubility
glacial acetic acid: 2 mg/mL
water: 2 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A selective, reversible, and substrate competitive inhibitor of protein kinase Cζ and protein kinase Cι (PKCζ/ι) isozymes.
Non-cell-permeable protein kinase Cζ and protein kinase Cι pseudosubstrate sequence peptide that can be used as a selective, reversible, and substrate competitive inhibitor PKCζ/ι in in vitro kinase assays.
Biochem/physiol Actions
Cell permeable: no
Primary Target
PKCζ
PKCζ
Product does not compete with ATP.
Reversible: yes
Warning
Toxicity: Standard Handling (A)
Sequence
H-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
Physical form
Supplied as a trifluoroacetate salt.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Sajan, M.P., et al. 1999. J. Biol. Chem.274, 30495.
Laudanna, C., et al. 1998. J. Biol. Chem.273, 30306.
Standaert, M.L., et al. 1997. J. Biol. Chem.272, 30075.
Laudanna, C., et al. 1998. J. Biol. Chem.273, 30306.
Standaert, M.L., et al. 1997. J. Biol. Chem.272, 30075.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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