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539604

Sigma-Aldrich

PKCη Pseudosubstrate Inhibitor, Myristoylated

The PKCη Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKCη. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

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Synonym(s):
PKCη Pseudosubstrate Inhibitor, Myristoylated, Myr-TRKRQRAMRRRVHQING-OH, Protein Kinase C η Pseudosubstrate Inhibitor, Myristoylated
Empirical Formula (Hill Notation):
C101H185N41O23S
Molecular Weight:
2373.88
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A cell-permeable, reversible, substrate competitive, and pseudosubstrate inhibitor of the protein kinase Cη isozyme. Useful for studies of PKCη function in intact cells.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
PKCν
Product competes with ATP.
Reversible: yes

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

Myr-Thr-Arg-Lys-Arg-Gln-Arg-Ala-Met-Arg-Arg-Arg-Val-His-Gln-Ile-Asn-Gly-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Osada, S., et al. 1992. Mol. Cell Biol.12, 3930.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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