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538909

Sigma-Aldrich

Prostaglandin D2

Major prostaglandin metabolite in brain and an important inflammatory mediator in mast cells.

Synonym(s):

Prostaglandin D2, PGD₂

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About This Item

Empirical Formula (Hill Notation):
C20H32O5
CAS Number:
Molecular Weight:
352.47
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

ethanol: 100 mg/mL
acetone: soluble
ethyl acetate: soluble
methanol: soluble

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1

InChI key

BHMBVRSPMRCCGG-OUTUXVNYSA-N

General description

Major prostaglandin metabolite in the brain and an important inflammatory mediator in mast cells. Neuromodulator that evokes nerve-mediated Cl- secretion. Stimulates adenylate cyclase.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Adenylate cyclase
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Horn, E.H., et al. 1995. Clin. Sci. 89, 91.
Frieling, T., et al. 1994. Am. J. Physiol. 266, G132.
Huttemeier, P.C., et al. 1993. Prostaglandins 45, 177.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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