Skip to Content
Merck
CN
All Photos(1)

Documents

538904

Sigma-Aldrich

Prostaglandin E2

Involved in vasodilator actions of kinins such as bradykinin.

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Prostaglandin E2, PGE₂
Empirical Formula (Hill Notation):
C20H32O5
CAS Number:
363-24-6
Molecular Weight:
352.47
MDL number:
MFCD00077861
UNSPSC Code:
12352211
NACRES:
NA.77

Quality Level

100

Assay

>98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to light yellow

solubility

acetone: soluble
ethanol: soluble
ethyl acetate: soluble
methanol: soluble

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+

InChI key

XEYBRNLFEZDVAW-RTYMFESYSA-N

General description

Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells

Warning

Toxicity: Harmful (C)

Other Notes

Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H360FD

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Arpan Acharya et al.
Journal of virology (2020-12-18)
HIV persists in cellular reservoirs despite effective combined antiretroviral therapy (cART) and there is viremia flare up upon therapy interruption. Opioids modulate the immune system and suppress antiviral gene responses, which significantly impact people living with HIV (PLWH). However, the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service