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524738

Sigma-Aldrich

Phosphodiesterase 5, Catalytic Domain, Human, Recombinant, S. frugiperda

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Synonym(s):
PDE5CAT, cGMP-Specific Phosphodiesterase 5, Catalytic Domain
UNSPSC Code:
12352202
NACRES:
NA.54

form

liquid

Quality Level

specific activity

≥0.5 U/μL

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Recombinant, human, phosphodiesterase 5 catalytic subunit expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will convert 1 pmol cGMP to GMP per min at 30°C, pH 7.5.

Physical form

In 150 mM NaCl, 10 mM Tris-HCl, 0.1% NP-40, pH 8.3.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.
Blount, M.A., et al. 2004. Mol. Pharmacol.66, 144.
Bakre, M.M., et al. 2000. J. Cell. Biochem.77, 159.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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