520224
PPACK, Dihydrochloride, Biotinylated
Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
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Synonym(s):
PPACK, Dihydrochloride, Biotinylated, Biotin-X-D-Phe-Pro-Arg-chloromethylketone, 2HCl
Empirical Formula (Hill Notation):
C43H70ClN10O7S · 2HCl
Molecular Weight:
979.52
UNSPSC Code:
12352200
Recommended Products
Quality Level
Assay
≥80% (HPLC and TLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−20°C
General description
Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: no
Target IC50: 110 nM against thrombin
Warning
Toxicity: Standard Handling (A)
Physical form
In 10 mM HCl.
Other Notes
Williams, E.B., et al. 1989. J. Biol. Chem.264, 7536.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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