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Safety Information

5120-OP

Millipore

Guanidine Isothiocyanate

OmniPur® Grade, >=99.0%, Protein denaturant

Synonym(s):

OmniPur® Guanidine Isothiocyanate, GITC, GTC, Guanidine thiocyanate, Guanidinium isothiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352107
NACRES:
NA.21

Quality Level

form

crystalline powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

shipped in

ambient

InChI

1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

InChI key

ZJYYHGLJYGJLLN-UHFFFAOYSA-N

General description

Protein denaturant used to inactivate RNases during isolation of RNA from cell lysates. Molecular biology grade.

Specifications:
A (280 nm, 70%, water): ≤0.8AU
Assay: ≥99.0%
DNase: None detected
Melting point: 118-121°C
Protease: None detected
RNase: None detected
Solubility (70%, water): To pass test





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Application


  • Collection and transportation of SARS-CoV-2 and influenza A virus diagnostic samples: Optimizing the usage of guanidine-based chaotropic salts for enhanced biosafety and viral genome preservation: This study emphasizes the critical role of guanidine isothiocyanate in the preservation of viral genomes during the collection and transport of diagnostic samples, thereby enhancing biosafety protocols in molecular biology applications (Komu JG et al., 2024).

  • How to better select SARS-CoV-2 preservation solution of virus nucleic acid testing: Focuses on optimizing viral RNA preservation using solutions containing guanidine isothiocyanate, contributing to more accurate diagnostics in virology (Duan X et al., 2023).

  • Visual Detection of Chicken Adulteration Based on a Lateral Flow Strip-PCR Strategy: Demonstrates the application of guanidine isothiocyanate in developing rapid diagnostic tools for food safety, enhancing the detection of adulterants in chicken products (Xu H et al., 2022).

  • Using discrete event simulation to optimize nucleic acid testing process for coronavirus disease 2019 (COVID-19): Describes how guanidine isothiocyanate enhances the efficiency of COVID-19 testing processes, aiding in faster diagnosis and better pandemic management (Guan W et al., 2022).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C

Supplementary Hazards

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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