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5.06382

Sigma-Aldrich

MPTP Hydrochloride

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Synonym(s):
MPTP Hydrochloride, Dopaminergic neurotoxin, MPTP
Empirical Formula (Hill Notation):
C12H15N · xHCl
CAS Number:
23007-85-4
Molecular Weight:
173.25 (free base basis)
MDL number:
MFCD00012790
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (TLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

water: 100 mg/mL

storage temp.

2-8°C

InChI

1S/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H

InChI key

KOWJANGMTAZWDT-UHFFFAOYSA-N

General description

A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.

Warning

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Langston, J. W., et al. 1985. Trends in Neurosci.8, 79.

Gabriel, T. L., et al. 1999. Nature Med.5, 1403.
Zhang, X., et al. 2010. J. Proteome Res.9, 1496.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301 - H370

Hazard Classifications

Acute Tox. 3 Oral - STOT SE 1

Target Organs

Nervous system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Certificates of Analysis (COA)

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