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5.05412

Sigma-Aldrich

1,1-Dimethyl-4-phenylpiperazinium iodide

Synonym(s):

1,1-Dimethyl-4-phenylpiperazinium iodide, 1,1-dimethyl-4-phenylpiperazinium, Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, (α3)2(β4)3 Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, Ganglionic Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP

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About This Item

Empirical Formula (Hill Notation):
C12H19IN2
CAS Number:
54-77-3
Molecular Weight:
318.20
MDL number:
MFCD00011976
UNSPSC Code:
12352200

Assay

≥98% (titration)

Quality Level

100

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

50% acetic acid: 50 mg/mL

storage temp.

2-8°C

InChI

1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1

InChI key

XFZJGFIKQCCLGK-UHFFFAOYSA-M

General description

An agonist selective for ganglionic subtype of acetylcholine receptors (nAChR) and acts as a ganglionic stimulant. At higher concentrations also inhibits the uptake of NE and 5-HT.

Biochem/physiol Actions

Primary Target
nAChR

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chen, R., et al., 1951. J. Pharmacol. Exp. Ther. 103.
Vizi, S., 1999. Brain Res. Brain Res. Rev.30, 219.
Prado. W., et al. 2004. Brain Res.1018, 272.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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