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Merck
CN

48-650MAG

MILLIPLEX® Human Src Family Kinase Phosphoprotein Panel

Premixed Human Src Family Kinase Phosphoprotein 8-Plex Cell Signaling Panel

Synonym(s):

Human Src Kinase Panel, Src Family Kinase Kit

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
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Product Name

MILLIPLEX® Human Src Family Kinase Phosphoprotein Panel, Premixed Human Src Family Kinase Phosphoprotein 8-Plex Cell Signaling Panel

Quality Level

species reactivity

human

manufacturer/tradename

Milliplex®

packaging

1 ea of

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

General description

The MILLIPLEX® 8-plex Human Src Family Kinase kit, phosphoprotein (pan Tyr), is used to detect tyrosine phosphorylation in Blk, Fgr, Fyn, Hck, Lck, Lyn, Src, and Yes in cell lysates using the Luminex® system. The detection assay is a rapid, convenient alternative to Western Blotting and immunoprecipitation procedures. Each kit has sufficient reagents for one 96 well plate assay.
Src family kinases (BLK, FGR, FYN, HCK, LCK, LYN, SRC, YES) are non-receptor tyrosine kinases involved in signal transduction for cell proliferation, differentiation, and immune responses. Phosphorylation at conserved tyrosine residues within their activation loops indicates kinase activation.

Packaging

96-well plate

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 8 analytes in cell lysate samples.Analytes Included: BLK (pY389), FGR (pY412), FYN (pY420), HCK (pY411), LCK (pY394), LYN (pY397), SRC (pY419), YES (pY426)Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).

Features and Benefits

  • Simultaneous detection of 8 phosphorylated Src family kinases
  • Comprehensive profiling of tyrosine kinase activity
  • Ideal for cancer, immune, and signal transduction research
  • High-throughput format reduces assay time and cost
  • Robust performance with minimal sample input

signalword

Danger

Storage Class

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Regulatory Information

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