444221
MMP-1/MMP-9 Substrate, Fluorogenic
An excellent quenched fluorescence substrate for MMP-1 and MMP-9.
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Synonym(s):
MMP-1/MMP-9 Substrate, Fluorogenic
Empirical Formula (Hill Notation):
C49H68N14O12S
Molecular Weight:
1077.22
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
yellow
solubility
50% acetic acid: 10 mg/mL
fluorescence
λex ~365 nm
λem ~450 nm
shipped in
ambient
storage temp.
−20°C
General description
An excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values. Excitation max: ~365 nm; emission max: ~450 nm.
An excellent quenched fluorescence substrate for MMP-1 and MMP-9. Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values.
Biochem/physiol Actions
Cell permeable: no
Primary Target
MMP-1, MMP-9
MMP-1, MMP-9
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Warning
Toxicity: Standard Handling (A)
Sequence
{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
Other Notes
Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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