444218
MMP-3 Inhibitor I
The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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Synonym(s):
MMP-3 Inhibitor I, Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor
Empirical Formula (Hill Notation):
C27H46N10O9S
Molecular Weight:
686.78
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
Inhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
Inhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
MMP-3
MMP-3
Product does not compete with ATP.
Reversible: no
Target IC50: 5 µM against MMP-3
Warning
Toxicity: Standard Handling (A)
Sequence
Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Physical form
Supplied as a trifluroacetate salt.
Reconstitution
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
Other Notes
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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