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444212

Sigma-Aldrich

MMP-2 Substrate, Fluorogenic

A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10⁵ M⁻¹s⁻¹).

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Synonym(s):
MMP-2 Substrate, Fluorogenic
Empirical Formula (Hill Notation):
C49H68N14O15
Molecular Weight:
1093.15
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

yellow

solubility

DMSO: 10 mg/mL

fluorescence

λex ~325 nm
λem ~393 nm

shipped in

ambient

storage temp.

−20°C

General description

A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 105 M-1s-1).
A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 105 M-1s-1; excitation maximum: ~325 nm; emission maximum: ~393 nm).

Biochem/physiol Actions

Cell permeable: no
Primary Target
A quenched fluorescence substrate for MMP-2 (gelatinase A)
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

MCA-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH₂[Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]

Other Notes

Murphy, G., et al. 1994. J. Biol. Chem. 269, 6632.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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