437641
Lipoproteins, High Density, Human Plasma
Synonym(s):
HDL
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.25
Assay
≥95% (of total lipoprotein content, electrophoresis)
Quality Level
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
shipped in
wet ice
storage temp.
2-8°C
General description
A 10 mg vial contains ~5 mg of protein.
Native high density lipoproteins from human plasma. Cholesterol-carrier lipoprotein that acts as scavenger of tissue cholesterol. Important in cholesterol efflux from tissues. Involved in return of cholesterol from the periphery to the liver for removal as bile acids. Composition: 55-45% lipid, 45-55% protein.
Native high density lipoproteins from human plasma. Cholesterol-carrier protein that acts as a scavenger of tissue cholesterol. Important in cholesterol efflux from tissues. Involved in return of cholesterol from the periphery to the liver for removal as bile acids. (Composition: 55-45% lipid, 45-55% protein. Note: 10 mg vial contains 5 mg of protein.)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Other Notes
Badimon, J.J., et al. 1992. Circulation 86, III86.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Xu Cui et al.
Stroke, 41(9), 2044-2049 (2010-07-31)
Niacin is the most effective medication in current clinical use for increasing high-density lipoprotein cholesterol. We tested the hypothesis that niacin treatment of stroke promotes synaptic plasticity and axon growth in the ischemic brain. Male Wistar rats were subjected to
Wojciech Paslawski et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(30), 15226-15235 (2019-07-05)
The progressive accumulation, aggregation, and spread of α-synuclein (αSN) are common hallmarks of Parkinson's disease (PD) pathology. Moreover, numerous proteins interact with αSN species, influencing its toxicity in the brain. In the present study, we extended analyses of αSN-interacting proteins
First-in-human autologous implantation of genetically modified adipocytes expressing LCAT for the treatment of familial LCAT deficiency.
Aso, et al.
Heliyon, 8, e11271-e11271 (2022)
Aynun N Begum et al.
Journal of Alzheimer's disease : JAD, 15(4), 625-640 (2008-12-20)
The rat amyloid-beta (Abeta) intracerebroventricular infusion can model aspects of Alzheimer's disease (AD) and has predicted efficacy of therapies such as ibuprofen and curcumin in transgenic mouse models. High density lipoprotein (HDL), a normal plasma carrier of Abeta, is used
Wei Shao et al.
The Journal of biological chemistry, 295(52), 18284-18300 (2020-10-29)
Oxygen regulates hypoxia-inducible factor (HIF) transcription factors to control cell metabolism, erythrogenesis, and angiogenesis. Whereas much has been elucidated about how oxygen regulates HIF, whether lipids affect HIF activity is un-known. Here, using cultured cells and two animal models, we
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